Prof. Roozbeh Ghaffari, Northwestern University

TITLE: Soft, Wearable Systems with Integrated Microfluidics and Biosensors for Remote Health Monitoring

ABSTRACT: Soft bio-electronics and microfluidics, enabled by recent advances in materials science and mechanics, can be designed with physical properties that approach the mechanical properties of human skin. These systems are referred to as epidermal electronics and epifluidics by virtue of their stretchable form factors and soft mechanics compared to conventional packaged electronics and sensors. Here, we present an overview of recent advances in novel materials, mechanics, and designs for emerging classes of fully-integrated epidermal electronics and soft microfluidic systems. These devices incorporate arrays of sensors, microfluidic channels and biochemical assays, configured in ultrathin, stretchable formats for continuous monitoring of electro-chemical signals and biophysical metrics. Quantitative analyses of strain distribution and circuit performances under mechanical stress highlight the utility of these wearable systems in clinical and home environments. We will conclude with representative examples of these wearable systems, which have entered the commercialization phase of deployment.

BIO: Dr. Ghaffari is co-founder and CEO of Epicore Biosystems, Inc., a company developing a proprietary wearable microfluidic sensing platform. He also serves as an Associate Research Professor in the Department of Biomedical Engineering at Northwestern University, and is Director of Translational Research at the Querrey-Simpson Institute for Bioelectronics. Dr. Roozbeh Ghaffari holds BS and MEng degrees in electrical engineering from the Massachusetts Institute of Technology. He received his PhD in biomedical engineering from the Harvard Medical School-MIT Program in Health Sciences and Technology. Upon completion of his PhD, Dr. Ghaffari co-founded MC10 Inc (acquired by Medidata Inc), and served as Chief Technology Officer. In this role, Dr. Ghaffari led the development and commercial launch of the BioStamp health monitoring platform. Dr. Ghaffari’s contributions in soft bioelectronics, micro/nano-scale systems, and auditory neuroscience research have been recognized with the Helen Carr Peake PhD Research Prize, MIT 100K Grand Prize, and MIT Technology Review Magazine’s Top 35 Innovators Under 35. He has published over 100 academic papers and is inventor on over 50 issued patents.
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